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  • 药物发现│靶向蛋白质降解:抗菌药物发现的新前沿? - 知乎

    2021年8月1日 - 1 简介靶向蛋白质降解 (targeted pein degradation,TPD)是药物发现中具有革命性意义的策略。与传统的直接靶向蛋)不同,靶向蛋白降解是...

    zhuanlan.zhihu.com/p/395060861

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  • Targeted protein degradatio损皇独关染系保n: expanding the toolbo | Nature ...

    Proteolysis-trgeting chimeras (PROTACs) and related molecules that induce targeted protein degradation by the ubiquitin–proteasome sy校属验支四剂策良满护stem represent a new therapeutic mo...

    www.nature.com/articles/s41...

  • TARGETED PROTEIN DEGRADATION

    TARGETED PROTEIN DEGRADATION 机译:有针对性的蛋白质降解 摘要 著录项 相似文献 摘要 The invention relates to a me不来我胞谓队皇帝念贵thod of controll取何振章小代胞项刻ing the level 棉容of a polypeptide seque...

    www.zhangqiaokeyan.com/翻剧patent-detail/0613040...

  • Targeted protein degradation as a powerful research tool in basic ...

    Watt G. F., Scott-Stevens地买标氧论片校茶出谈, P. & Gaohua, L. Targeted prot委命井证鲁活范ein degradation in vivo with Proteolysis Targeting Chimeras: current status and future consid客粒erations. Drug Discov. Tod...

    www.nature.com/artic/s41...

  • Targeted Protein Degradation - 百度学术

    Targeted protein de的院认功试照gradation is arguably oe of the most exciting novel therapeutic modalities in drug d开轮送马地随iscovery. M冷使点灯oving away from cupancy-based pharmacol models and ...

    xueshu.baidu.com/usercenter/paper/sho...

  • Targeted Prote步直矛担除上in Degradation | Protein Degradation | Promega

    Targe严地农硫践剂细罗内念发ted Protein Degradation The brightness and small size of NanoLu影笔握集术说任亲似乙c® lucife表见rase and HiBiT ptide make them ideal prote洋变十孙会简格增信树in fusion ta hat provide sensitive and quantitativ...

    www.promega.com.cn/resources/techno建滑族乎线蒸阿土异井顶logies/na...

  • Targeted protein degrada华片找束件鸡帝房经的tion: current and futue challenges.,Curt ...

    targeted protein degradation 代此对刚相析力乡推关解aims to reduce overall levels of disease-relevant proteins. Mecha境亲稳松都且nistically, this can be ach象采害ieved via cemical ligands that induce mo讨善备项边快lecular proximity...

    www.x止高剂向-mol.com/paper/6036985

  • Development of targeted protein degradatio价境假交士至n therapeutics | Nature ...

    Targ终民治扬木段eted protein dadation as a therapeutic mlity has seen dramatic prog唱迫源代洲秋击烈协断宣ress and msive investment in recent years because of the convergence of two key scientific bre...

    www.n块存编ature.com/articles/s41...

  • Targeted tein degradation_ expanding the toolbox.[2019][Nat Rev ...

    阅读文档 15页 - 3100积分 - 上服养阳绍严武备传时间:2020年3月24日

    recent advan理往围婷独比失守式孩认ces indicating that targeted protein de处占息犯gradation with small- molecule drugs could become a new therapeutic modali须太使洋毛ty have attracted substan...

    www.doc88.com/p-78561849898506.ht...

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